With an availability of a single medical therapy, ischaemic stroke continues to be one of the leading causes of mortality and morbidity in the World. Hence it is of paramount importance to find alternative therapies that can simultaneously affect various molecular mechanisms and demonstrate long term effects. Hypothermia has long been considered as a therapeutic option in preventing ischaemia-mediated brain damage and is already in place as an efficacious neuroprotective treatment regimen in neonatal hypoxic encephalopathy and in adults after cardiac arrest. However, before becoming an approved treatment for stroke, a comprehensive understanding of molecular mechanisms involved in its putative beneficial effects during or after ischaemic cerebral damage is needed. Furthermore, strong evidence on the optimal conditions in that hypothermic therapy may be administered and a thorough understanding of the associated potential complications are also required. This review paper initially discusses the optimal conditions in which hypothermic therapy may be safely applied before pointing out the systematic complications that may emerge from this treatment.

Stroke Research & Therapy  is an international open access peer-reviewed journal dedicated to disseminate the basic and clinical studies of Stroke research through its publications. The journal uses Editorial Manager System for quality peer review process. Review processing is performed by the editorial board members of Journal

We welcome you to be a part of our medical Journey by contributing your outstanding research work with us. A standard editorial tracking system is utilized for manuscript submission, review and tracking for quality and quick review processing, which can be securely accessed by the authors, reviewers and editors for monitoring and tracking their articles

Media Contact:

Anna Watson

Editorial Assistant

Stroke Research and Therapy Journal

E-mail: stroke@peerjournal.org

Whatsapp No: +1-579-679-8957